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Recent Publications

Quarterly Updates: Recent Publications from CF@LANTA and CF-AIR Investigators

A   novel drug series optimized to address cystic fibrosis and other CFTR   deficiency diseases of human airways. 

Rab A, Hong JS, Manfredi C, Joshi D, Ponnaluri S, Tracy   WF, Luo Y, Yang X, Kolykhalov AA, Davies HML, Sorscher EJ.

NPJ Drug Discov. 2025 Nov 3;2(1):27. doi:   10.1038/s44386-025-00026-1.

PMID: 42380489      Free PMC   article. 

 

Vanadyl   sulfate supplementation alters the intestinal microbiome and bile acid   metabolism. 

He X, Dennis KK, Jarrell ZR, Ly VT, Go YM, Jones DP.

Toxicol Appl Pharmacol. 2025 Dec;505:117548. doi:   10.1016/j.taap.2025.117548. Epub 2025 Sep 11.

PMID: 40945867     

 

Single-cell   multiomic analysis of mesenchymal cells reveals molecular signatures and   regulators of lung allograft fibrosis. 

Lu L, McLinden AP, Walker NM, Vittal R, Wang Y, Fattahi F,   Russell ST, Combs MP, Welch JD, Lama VN.

JCI Insight. 2026 Apr 23;11(13):e196651. doi:   10.1172/jci.insight.196651. eCollection 2026 Jul 8.

PMID: 42044158     

 

Active   Chlorine Antiseptics in Wound Care: Recent Advances and Perspectives for   Military Medicine. 

Murashevych B, Stepanskyi D, Wuest WM, Jakobsen TH.

APMIS. 2026 Jun;134(6):e70228. doi: 10.1111/apm.70228.

PMID: 42230156      Review.       

 

Beyond   The Nucleus: Translating Engineered Protein Localization To Chromatin   Modifying Enzymes. 

Hirani Z, Tirouvanziam R, Haynes KA.

Curr Opin Biomed Eng. 2026 Jun;38:100668. doi:   10.1016/j.cobme.2026.100668. Epub 2026 May 14.

PMID: 42389724      Free PMC   article. 

 

Clinical   outcomes in food allergy: Implications for patients, clinicians, and health   systems. 

Ezhuthachan ID, Cheng AM, Bird JA, Bingemann TA, Järvinen   KM, Ekici S, Shreffler WG, Vickery BP.

Ann Allergy Asthma Immunol. 2026 Jun;136(6):630-638. doi:   10.1016/j.anai.2026.03.009. Epub 2026 Mar 19.

PMID: 41862017      Review.       

 

The   Science and Art of Neonatal Respiratory Care. 

Jain L.

Clin Perinatol. 2026 Jun;53(2):xvii-xix. doi:   10.1016/j.clp.2026.03.007. Epub 2026 Apr 16.

PMID: 42276729      No abstract   available.

 

Evaluating   the effects of CD8/CD4 on T cell function in terms of TCR-pMHC-coreceptor   catch and slip bonds. 

Travaglino S, Kazemipour Ashkezari AH, Li M, Watson VE,   Cong P, Doudy L, Choi HK, Zhu C.

Front Immunol. 2026 Jun 5;17:1757198. doi:   10.3389/fimmu.2026.1757198. eCollection 2026.

PMID: 42327727      Free PMC   article. 

 

Structural   Diversity and Analytical Characterization of Acylhomocarnitines. 

Weinberg J, Crandall WJ, Jarrell ZR, Lim G, Liu K, Lee HY,   Patel S, Gacasan CA, Go YM, Jones DP.

J Proteome Res. 2026 Jun 5;25(6):3054-3065. doi:   10.1021/acs.jproteome.5c01255. Epub 2026 May 13.

PMID: 42127330      Free PMC   article. 

 

Myeloid-avid   mammalian target of rapamycin-inhibiting nanobiologic attenuates allograft   fibrosis after lung transplantation. 

Mineura K, Liu CR, Amrute JM, Kawana S, Elmenshawy FH,   Perez JL, Lounsbery-Scaife W, Poddar N, Nunna V, Li W, Terada Y, Meadows A,   Heo GS, Wang W, Davighi MG, Morla-Folch J, Park S, Laghlali G, Burgess E,   Schotsaert M, Liu Y, Lavine KJ, Ritter JH, Lama VN, Brody SL, Nava RG, Gelman   AE, Krupnick AS, Perez-Rodriguez L, Hasson D, Teunissen AJP, Ochando J,   Kreisel D.

Am J Transplant. 2026 Jun 6:S1600-6135(26)02582-7. doi:   10.1016/j.ajt.2026.05.2303. Online ahead of print.

PMID: 42252026     

 

Prediction   of Mesenchymal Stromal Cell Immune Suppression Using Live Imaging in a   Three-Dimensional Microfluidic Device. 

Priyadarshani P, Schneider RS, Rui K, García AJ, Mortensen   LJ.

ACS Biomater Sci Eng. 2026 Jun 8. doi:   10.1021/acsbiomaterials.6c00109. Online ahead of print.

PMID: 42257541     

 

Profiling   the CFTR Variant Selectivity and Off-Target Interactions of VX-121. 

Jhangiani AR, Olson JA 3rd, Tedman A, Foye C, Jackson JJ,   Winters AG, White JA, Perfetti M, Abell GM, Cameron CD, Arifova L, Corman B,   Paul Robinson J, Kuntz CP, Ledwitch KV, Meiler J, Oliver KE, Plate L,   Schlebach JP.

bioRxiv [Preprint]. 2026 Jun 8:2026.06.01.729306. doi:   10.64898/2026.06.01.729306.

PMID: 42282787      Free PMC   article.      Preprint.     

 

The   Wheezing, Asthma and Viral effects on the Epithelial Structure and function   (WAVES) birth cohort study: rationale, design and methods to understand   airway development and the role of early-life respiratory viral infections on   childhood asthma inception. 

Hartert T, Rosas-Salazar C, Newcomb DC, Snyder BM,   Berdnikovs S, McKennan C, Osmundson S, Liu Z, Tafoya E, Folad W, Simon P,   Reiss S, Poleon K, Cephus JY, Kuehnle SN, McKernan KE, Ma S, Anderson LJ,   Gebretsadik T.

BMJ Open Respir Res. 2026 Jun 9;13(1):e004049. doi:   10.1136/bmjresp-2025-004049.

PMID: 42264881      Free PMC   article. 

 

Elexacaftor-Tezacaftor-Ivacaftor   for Individuals with Residual CFTR Activity: An Open-Label, Nonrandomized   Clinical Trial. 

Linnemann RW, Solomon GM, Westbrook AL, Rich R, Streby A,   Hunter E, Rab A, Bai S, Mcnicholas CM, Hong JS, Manfredi C, Hunt WR, Stecenko   AA, Barillà C, Suzuki S, Davis BR, Sorscher EJ.

Ann Am Thorac Soc. 2026 Jun 10:aaoag136. doi:   10.1093/annalsats/aaoag136. Online ahead of print.

PMID: 42271629      No abstract   available.

 

The   Guild Model of CF Airway Microbial Ecology. 

Dunham SJB, Willkeen GA, Darby B, Corley JM, Hahn A,   Klapper I, Bean HD, Caverly LJ, Thornton CS, Martin C, Quinn RA, Widder S,   Bailey BA, Wagner BD, Garg N, Planet PJ, Hunter RC, LiPuma JJ, Rohwer F,   Whiteson KL.

mBio. 2026 Jun 10;17(6):e0366825. doi:   10.1128/mbio.03668-25. Epub 2026 Apr 30.

PMID: 42059556      Free PMC   article. 

 

Host   and antibiotic jointly select for greater virulence in Staphylococcus   aureus. 

Su M, Hoang KL, Penley M, Davis MH, Gresham JD, Morran LT,   Read TD.

Elife. 2026 Jun 16;14:RP107936. doi: 10.7554/eLife.107936.

PMID: 42299869      Free PMC   article. 

 

Concise   synthesis of simplified aogacillin analogs reveals innate reactivity and   synergy with aminoglycosides. 

LeBlanc AR, Smith JR, Isakov AJ, Bacsa J, Wuest WM.

Chem Sci. 2026 Jun 19. doi: 10.1039/d6sc04046b. Online   ahead of print.

PMID: 42375175      Free PMC   article. 

 

A   polyvalent phage shapes bacterial dynamics. 

Crisan CV, Van Tyne D, Goldberg JB.

J Virol. 2026 Jun 23;100(6):e0136325. doi:   10.1128/jvi.01363-25. Epub 2026 May 19.

PMID: 42153737      Free PMC   article. 

 

Mass   spectrometry as the unifying force in natural product sciences. 

Beniddir MA, Cech NB, Linington R, Garg N.

Nat Prod Rep. 2026 Jun 26;43(6):1070-1072. doi:   10.1039/d6np90018f.

PMID: 42300973      No abstract   available. 

 

Mass   spectrometry-based metabolomics approaches to interrogate host-microbiome   interactions in mammalian systems. 

Kulkarni AS, Carrara GMP, Jin J, Laro J, Peramuna T,   McCall LI, Garg N.

Nat Prod Rep. 2026 Jun 26;43(6):1078-1105. doi:   10.1039/d5np00021a.

PMID: 40521991      Free PMC   article.      Review.     

 

Healthcare   priorities and needs for LGBTQIA+ people with cystic fibrosis: A concept   mapping study. 

Kidd KM, Salyer RE, Rashid SJ, Mitchell AS, Alpern A,   Greenberg J, Stransky OM, Prangley A, Tangpricha V, Sequeira GM, Lunn MR,   Palla J, Cevallos L, Jain R, Deci SE, Kahn NF, Nowakowski AXCH, Sender AI;   Brandon Wright, PRIDE CF Community Partner Group; PRIDE CF Concept Mapping   Participants; Sawicki GS, Kazmerski TM.

J Cyst Fibros. 2026 Jun 29:S1569-1993(26)01647-4. doi:   10.1016/j.jcf.2026.06.006. Online ahead of print.

PMID: 42373328     

 

Development   of a microneedle patch for delivery of mRNA-lipid nanoparticles. 

Sakers SH, Reddy BPK, Fiduccia G, Byrne KE, Stén I, Kim J,   Radmand A, Dahlman JE, Prausnitz MR.

Drug Deliv Transl Res. 2026 Jul;16(7):2256-2271. doi:   10.1007/s13346-025-01964-z. Epub 2025 Sep 2.

PMID: 40892321      Free PMC   article. 

 

Distinct   signaling mechanisms and proteome phenotypes are elicited by   compartment-specific genetic defects of copper homeostasis. 

Lane AR, Gonzalez N, Gokhale A, Zlatic SA, Allen BM, Scher   NE, Roberts AM, Duong DM, Roberts BR, Vrailas-Mortimer AD, Werner E, Faundez   V.

Mol Biol Cell. 2026 Jul;37(7):ar61. doi:   10.1091/mbc.E26-01-0021. Epub 2026 Jun 16.

PMID: 42126960     

 

From   the pages of AllergyWatch. 

Joshi SR, Chow T, Lee GB.

Ann Allergy Asthma Immunol. 2026 Jul;137(1):124-125. doi:   10.1016/j.anai.2026.05.013.

PMID: 42362331      No abstract   available.

 

Global   Group Testing and Screening With Dynamic Effects. 

Cui Y, Peng L.

Stat Sin. 2026 Jul;36(3):1279-1300. doi:   10.5705/ss.202023.0285.

PMID: 42422231      Free PMC   article. 

 

"It   Felt Like Throwing in the Towel": Family Caregiver Perspectives on   End-of-Life Decision Making in Chronic Obstructive Pulmonary Disease. 

Smirnova N, Batieste T, Cross SH, Jamdar S, Peterson CS,   Vaughan CP, Kavalieratos D.

J Palliat Med. 2026 Jul;29(7):946-950. doi:   10.1177/10966218261443102. Epub 2026 Apr 13.

PMID: 41974615      Free PMC   article. 

 

A   microgel bone marrow model of mesenchymal stromal cell paracrine signaling   supporting hematopoietic stem cell retention. 

Thompson GB, Kuo KM, García AJ, Harley BAC.

Acta Biomater. 2026 Jul;218:338-349. doi:   10.1016/j.actbio.2026.06.009. Epub 2026 Jun 4.

PMID: 42248284     

 

Updates   in Cystic Fibrosis Bone Disease in Adults. 

Runchey S, Harindhanavudhi T, Wu M, Tangpricha V.

Endocr Pract. 2026 Jul;32(7):1139-1146. doi:   10.1016/j.eprac.2026.03.004. Epub 2026 Mar 25.

PMID: 41895691      Free PMC   article.      Review.     

 

A   prospective study of high-impact chronic pain in sickle cell disease: the   Sickle Pain-Related Impact (SPiRIt) study. 

Jagtiani A, Hawk A, Sinha C, Gillespie SE, Mirbeyk M,   Burke R, Ifendu N, Reese S, Howard V, Boguslawski S, Thompson O, Ikkurthy N,   El Rassi F, Smith WR, Krishnamurti L, Sil S, Bakshi N.

Pain. 2026 Jul 1;167(7):1578-1592. doi:   10.1097/j.pain.0000000000003956. Epub 2026 May 8.

PMID: 42017907     

 

Untargeted   serum metabolomics and air pollution in Parkinson's disease. 

Kwon D, Paul KC, Lin Y, Thordarson DN, Wu J, Su J, Jones   DP, Bronstein JM, Ritz B.

NPJ Parkinsons Dis. 2026 Jul 1. doi:   10.1038/s41531-026-01451-3. Online ahead of print.

PMID: 42386730     

 

Mucin-induced   metabolic reprogramming in Pseudomonas aeruginosa clinical isolates. 

Islam MM, Kolling GL, Goldberg JB, Ribbeck K, Papin JA.

mSystems. 2026 Jul 2:e0058026. doi:   10.1128/msystems.00580-26. Online ahead of print.

PMID: 42390224     

 

Sparse   CCA-based mediation analysis with high-dimensional exposures and mediators. 

Li X, Kong M, Smith MR, Liang Y, Teeny S, Ly VT, Go YM,   Samala N, Jones DP, Luo J, Watson WH, McClain CJ, Vatsalya V, Szabo G,   Dasarathy S, Mitchell M, Nagy LE, Barton B, Cave MC, Jiang H.

Bioinformatics. 2026 Jul 2;42(7):btag474. doi:   10.1093/bioinformatics/btag474.

PMID: 42378448      Free PMC   article. 

 

Intraspecific   diversity of Staphylococcus aureus populations isolated from cystic   fibrosis respiratory infections. 

Alexander AM, Loo HQ, Askew L, Raghuram V, Satola SW, Read   TD, Goldberg JB.

Microbiol Spectr. 2026 Jul 6:e0036726. doi:   10.1128/spectrum.00367-26. Online ahead of print.

PMID: 42405791     

 

Scholarly   Skills Series: How to Succeed in Writing Case Reports. 

Lal A, Pinto Taylor E, Kavalieratos D, Robbins-Welty GA.

J Palliat Med. 2026 Jul 7:10966218261465073. doi:   10.1177/10966218261465073. Online ahead of print.

PMID: 42415542     

 

Effects   of a low-glycaemic, moderately carbohydrate-restricted diet on hepatic lipid   content and insulin sensitivity in adolescents with metabolic   dysfunction-associated steatotic liver disease: protocol of a 6-month   family-based, randomised controlled trial. 

Drake C, Goss AM, Gower BA, Ashraf A, Alvarez J, Bolding   M, Bril F, Cedillo Y, Luzuriaga-McPherson A, Hanson R.

Br J Nutr. 2026 Jul 13:1-8. doi:   10.1017/S0007114526108058. Online ahead of print.

PMID: 42438408     

 

Pervasive   interactions between exposures and polygenic risk can inform more effective   clinical and behavioral interventions. 

Nagpal S, Gibson G.

Nat Genet. 2026 Jul 13. doi: 10.1038/s41588-026-02674-z.   Online ahead of print.

PMID: 42443528      

 

Biosocial   influences of gender identity and geography on mucosal microbial phenotypes. 

Van Doren VE, Smith SA, Grimsley Ackerley C, Keith J,   Arthur RA, Claussen H, Murray P, Tangpricha V, Hu YJ, Su C, He M, Kelley CF.

Commun Med (Lond). 2026 Jul 14. doi:   10.1038/s43856-026-01780-7. Online ahead of print.

PMID: 42448874     

 

I-STRONG:   an integrative, multicomponent treatment approach for chronic pain in   pediatric sickle cell disease. 

Sil S, Mooney JT, Adkins TR, Sinha C, Nuñez MA, Busbee A,   Dampier C, Bai S, Crosby LE, Thomas S, Beasley K, Lang AC, Murphy B, Williams   J, Batts K, Kurzhals A, Quinn CT, Myer GD, Bakshi N, Kesar T, Kashikar-Zuck   S.

Blood Adv. 2026 Jul 14;10(13):4617-4629. doi:   10.1182/bloodadvances.2025018952.

PMID: 42024471      Free PMC   article.      Clinical Trial.        

  

Non-uniform   susceptibility profiles observed in Staphylococcus aureus, Pseudomonas   aeruginosa, and Acinetobacter baumannii toward both front-line and   novel cationic biocides with diverse structural compositions. 

Vargas-Cuebas GG, Minbiole KPC, Wuest WM.

Microbiol Spectr. 2026 Jul 16:e0104126. doi:   10.1128/spectrum.01041-26. Online ahead of print.

PMID: 42461033     

 

Factors   governing the response of Pseudomonas aeruginosa to hypothiocyanous   acid. 

VanDrisse CM, Swenson C, Hudock KM, Stecenko AA, Rada B.

Front Cell Infect Microbiol. 2026 Jul 17;16:1878666. doi:   10.3389/fcimb.2026.1878666. eCollection 2026.

PMID: 42539461      Free PMC   article.      Review.      

 

Radiomics   of the Airway (RadAr): Multi-Scale Airway Phenotyping for Disease   Characterization on Routine CT Imaging. 

Mutha P, Lee J, Silva GL, Dreihuys B, Healy Z, Mummy D,   Kaul B, Ram S, Tirouvanziam R, Guglani L, Madabhushi A.

medRxiv [Preprint]. 2026 Jul 21:2026.07.19.26358441. doi:   10.64898/2026.07.19.26358441.

PMID: 42538919      Free PMC   article.      Preprint.      

 

Mechanistic   Insights into Redox-Dependent Macropinocytosis in Primary Human Neutrophils. 

Addo SA, Babay I, Sreekumar A, Sloan D, Roy T, Sudha A,   Thomas J, Harris RA, Benyó Z, Csányi G.

Antioxidants (Basel). 2026 Jul 21;15(7):904. doi:   10.3390/antiox15070904.

PMID: 42510635      Free PMC   article. 

 

Mucin-induced   metabolic reprogramming in Pseudomonas aeruginosa clinical isolates. 

Islam MM, Kolling GL, Goldberg JB, Ribbeck K, Papin JA.

mSystems. 2026 Jul 21;11(7):e0058026. doi:   10.1128/msystems.00580-26. Epub 2026 Jul 2.

PMID: 42390224      Free PMC   article. 

 

Correcting   serum phosphate homeostasis does not alleviate the health dangers of high   phosphate consumption. 

Arnst JL, D Alappan U, Viggeswarapu M, Beck GR Jr.

J Transl Med. 2026 Jul 22. doi:   10.1186/s12967-026-08624-x. Online ahead of print.

PMID: 42482096     

 

A   Novel Tool for Assessing the Content and Quality of Goals of Care   Documentation. 

Shrake K, Cook T, Kavalieratos D, McLouth C, Schell J,   Arnold R.

J Palliat Med. 2026 Jul 24:10966218261472172. doi:   10.1177/10966218261472172. Online ahead of print.

PMID: 42499223     

 

SynNotch   receptors for visualizing immunoreceptor force transmission and downstream   signaling in vivo. 

Li M, Lyu J, Li K, Dravid A, Balasubramani D, Ashkezari   AHK, Choi HK, Kwong GA, Singh A, Zhu C.

bioRxiv [Preprint]. 2026 Jul 25:2026.06.26.734558. doi:   10.64898/2026.06.26.734558.

PMID: 42427662      Free PMC   article.      Preprint.     

 

Treatment   of Multifood Allergy With Omalizumab or Multiallergen Oral Immunotherapy: A   Randomized Clinical Trial. 

Wood RA, Togias A, Burk CM, Sindher S, Dantzer JA,   Sicherer S, Wang J, Shreffler W, Kim E, Keet C, Kulis M, Jones S, Scurlock A,   Leung D, Lanser B, Bird JA, Parrish C, Vickery BP, Mudd K, Long A,   Ezhuthachan I, Spergel J, Brown-Whitehorn T, Ligueros-Saylan M, Iqbal A,   Cameron B, Huckabee CM, Yovetich N, Rogers N, Ozanne MV, Poyser J, Veri M,   Hamrah SD, Lin AA, Wheatley LM, Chinthrajah RS.

JAMA Pediatr. 2026 Jul 27:e262910. doi:   10.1001/jamapediatrics.2026.2910. Online ahead of print.

PMID: 42507431      Free PMC   article. 

 

Immune   cells harbor their own microbiome-derived metabolome: a new layer of   immunometabolic regulation. 

Daley-Bauer L, Flantzer L, Kyu S, Godoy A, Weinberg J,   Marconi VC, Jones DP, Younes SA.

Front Immunol. 2026 Jul 28;17:1852583. doi:   10.3389/fimmu.2026.1852583. eCollection 2026.

PMID: 42582102      Free PMC   article.      Review.     

 

LRRK2   G2019S reprograms innate and adaptive immunity to drive context-dependent   host defense outcomes. 

Merchak AR, Herrick MK, Houser MC, Moustafa DA, Goldberg   JB, Boss JM, Kohlmeier J, Cook DM, Keating CE, Chang J, West AB, Tansey MG.

Front Cell Neurosci. 2026 Jul 29;20:1860967. doi:   10.3389/fncel.2026.1860967. eCollection 2026.

PMID: 42591263      Free PMC   article. 

 

The   role of sweat chloride in determining CFTR protein restoration in people with   cystic fibrosis. 

Zemanick ET, Graeber SY, Castellani C, Cutting GR, Fajac   I, Konstan MW, Linnemann RW, McKone EF, Metcalf A, Solomon GM, Taylor-Cousar   JL, Mayer-Hamblett N, Mall MA.

Lancet Respir Med. 2026 Aug;14(8):704-716. doi:   10.1016/S2213-2600(26)00159-1. Epub 2026 Jul 13.

PMID: 42442377      Review.        

 

Safety   of Sildenafil in Premature Infants with Severe Bronchopulmonary Dysplasia   (SILDI-SAFE): A Randomized Controlled Trial. 

Jackson WM, Foote HP, Stephenson N, Kemp SM, Moore RT,   Nitkin CR, Stewart D, Pryhuber GS, Berger JT, Shukla A, England A, Ford SM,   Parton LA, Check JF, Hanna MH, Lagoski M, Krishnan R, Leeman KT, Vyas-Read S,   Hudak ML, Katheria AC, Pillers DM, Ji J, Banfro F, Nelin LD, McCulloch M,   Ahmad K, Laughon MM, Hornik CP; SILDI-SAFE Study Group.

J Pediatr. 2026 Aug;295:115147. doi:   10.1016/j.jpeds.2026.115147. Epub 2026 May 7.

PMID: 42105936      Free PMC   article.      Clinical Trial.       

 

Subtypes   of Type 2 Diabetes and Prediabetes: Mortality and Excess Life Lost in South   Asians. 

Jagannathan R, Kondal D, Tiwari P, Deepa M, Gujral UP,   Patel SA, Mohan S, Anjana RM, Staimez LR, Gupta R, Beyh YS, Oguntade AS,   Chang HH, Ali MK, Quyyumi A, Sun YV, Prabhakaran D, Tandon N, Mohan V,   Narayan KMV.

Diabetes Care. 2026 Aug 1;49(8):1330-1338. doi:   10.2337/dc26-0043.

PMID: 42102359      Free PMC   article. 

  

Infant   Infection With Respiratory Syncytial Virus Genotypes and Subsequent Childhood   Asthma Risk. 

Rosas-Salazar C, Gebretsadik T, Chappell JD, Peebles RS   Jr, Dupont WD, Shilts MH, Jadhao SJ, Anderson LJ, Das SR, Hartert TV.

J Infect Dis. 2026 Aug 3;234(1):e34-e39. doi:   10.1093/infdis/jiag104.

PMID: 41773827      Free PMC   article. 

 

Intraspecific   diversity of Staphylococcus aureus populations isolated from cystic   fibrosis respiratory infections. 

Alexander AM, Loo HQ, Askew L, Raghuram V, Satola SW, Read   TD, Goldberg JB.

Microbiol Spectr. 2026 Aug 4;14(8):e0036726. doi:   10.1128/spectrum.00367-26. Epub 2026 Jul 6.

PMID: 42405791      Free PMC   article. 

 

Growing   Staphylococcus aureus in synthetic cystic fibrosis medium promotes   colonization in a murine pneumonia model. 

Luu JM, Moore IN, Moustafa DA, Goldberg JB.

Infect Immun. 2026 Aug 6:e0028326. doi:   10.1128/iai.00283-26. Online ahead of print.

PMID: 42560312     

 

Single-cell   RNA sequencing reveals dysregulation of innate immune signaling in early-life   respiratory syncytial virus infection with subsequent low-level cadmium   exposure. 

Jarrell ZR, Lee HY, Jeon J, Lim G, Lee CM, Kang SM, Chen   Y, Jones DP, Go YM.

Toxicol Rep. 2026 Aug 6;17:102325. doi:   10.1016/j.toxrep.2026.102325. eCollection 2026 Dec.

PMID: 42620461      Free PMC   article. 

 

Suppressive   genetic interactions between haploinsufficient mitochondrial genes encoded in   the 22q11.2 microdeletion locus define brain and cardiac phenotypes. 

Wynne M, Zlatic SA, Park AS, Crocker A, Mendez-Vazquez H,   Liporace E, Gokhale A, Tower-Gilchrist C, Robinette M, Purcell RH, Bassell   GJ, Werner E, Kwong JQ, Faundez V.

Hum Mol Genet. 2026 Aug 10;35(17):ddag073. doi:   10.1093/hmg/ddag073.

PMID: 42574252     

 

Non-invasive   nanoparticle barcoding in nonhuman primates. 

Jang B, Zenhausern R, Lian L, Gentry K, Abbas AM, Rudden   S, Shin YJ, Doan J, Loughrey D, Curran EH, Wood JS, Stammen RL, Johnson RP,   Kim H, Dahlman JE.

Nat Biotechnol. 2026 Aug 11. doi:   10.1038/s41587-026-03262-6. Online ahead of print.

PMID: 42581234     

 

Reply:   Statistical Fragility and Methodological Constraints in Metabolomic Mediation   of Air Pollution and Cardiovascular Risk. 

Liu C, Chang HH, Jones D, Quyyumi A, Liang D.

JACC Adv. 2026 Aug 12;5(9):103149. doi:   10.1016/j.jacadv.2026.103149. Online ahead of print.

PMID: 42585852      Free PMC   article.      No abstract available.

 

Low   Cord Blood Titers Are Associated with Prolonged Maternal RSV Antibody   Half-Lives in Preterm Infants. 

Willemsen JE, Phijffer EWEM, Wildenbeest JG, Anderson LJ,   Ha B, Sankaranarayanan R, Groenendaal F, Bloemenkamp KWM, Borghans JAM,   Drylewicz J, Bont L.

J Infect Dis. 2026 Aug 13:jiag417. doi:   10.1093/infdis/jiag417. Online ahead of print.

PMID: 42594156      

 

Pharmacoexposomics:   The Environmental Complement to Pharmacogenomics to Advance Precision   Medicine. 

Reho P, Thaker VV, Athreya AP, Cremers S, Go YM, Hripcsak   G, Hu X, Jones DP, Kim SM, Lazaridis KN, Li S, Pennell KD, Singh RR, Walker   DI, Patel CJ, Miller GW, IndiPHARM Consortium.

Annu Rev Pharmacol Toxicol. 2026 Aug 13. doi:   10.1146/annurev-pharmtox-062624-113658. Online ahead of print.

PMID: 42594291      Review.       

 

Ingestible   probes for breath-based monitoring of drug-metabolizing activity from the   microbiome. 

Manickam VA, Kimpling CE, Le KN, Troussé ME, Kang A, Patel   AS, Chan LW.

Sci Adv. 2026 Aug 14;12(33):eaee2632. doi:   10.1126/sciadv.aee2632. Epub 2026 Aug 14.

PMID: 42600024      Free PMC   article. 

 

Inhaled   dry powders of mRNA polyplexes prepared by thin-film freeze-drying. 

Giri BR, Jung Y, Moon C, Ek P, Jeong H, Southard B, Hwang   J, Patel CJ, Peck HE, Owens DE 3rd, Williams RO 3rd, Davenport GJ, Santangelo   PJ, Zurla C, Cui Z.

Int J Pharm. 2026 Aug 17;703:127319. doi:   10.1016/j.ijpharm.2026.127319. Online ahead of print.

PMID: 42607969     

 

Arginine   Therapy for Sickle Cell Disease Acute Pain Episodes: The STArT Randomized   Clinical Trial. 

Morris CR, Hatabah D, Korman R, Ahmad FA, Airewele G,   Akinsola B, Alzraikat N, Bakshi N, Brousseau DC, Brown K, Campbell AD, Casper   TC, Chang TP, Chumpitazi CE, Cohen D, Coleman KD, Covelo L, Cruz AT, Denton   C, Ellison AM, Fields M, Jensen H, Leibovich S, Rees CA, Remiker A, Singh N,   Thompson A, Vichinsky E, Villella A, Wilkinson H, Wynn B, Dampier C;   Pediatric Emergency Care Applied Research Network (PECARN).

JAMA. 2026 Aug 19:e2613310. doi: 10.1001/jama.2026.13310.   Online ahead of print.

PMID: 42616542     

 

Azithromycin   for Preschoolers with Wheezing in the Emergency Department. 

Denninghoff KR, Casper TC, Zorc JJ, Ruddy RM, Satola S,   Wendt WJ, Morris CR, Tavarez MM, Lipshaw MJ, Kwok MY, Nesiama JO, Nelson KA,   Webb M, Martinez FD; PECARN AZ-SWED Trial Study Group.

N Engl J Med. 2026 Aug 20;395(8):753-764. doi:   10.1056/NEJMoa2516505. Epub 2026 May 18.

PMID: 42149992      Free PMC   article.      Clinical Trial.       

 

Placental   Histopathology and Transplacental Transfer of RSV-specific Neutralizing   Antibodies The Silver Study. 

Phijffer EWEM, Willemsen J, Wildenbeest JG, Anderson LJ,   Bloemenkamp KWM, Groenendaal F, Nikkels PGJ, Bont LJ.

Pediatr Infect Dis J. 2026 Aug 20. doi:   10.1097/INF.0000000000005363. Online ahead of print.

PMID: 42618978     

 

Navigating   physician-scientist careers: insights from American Board of Internal   Medicine Research Pathway graduates. 

Gallagher EJ, Kazmierczak BI, Kisielewski M, Schoettler N,   Steer CJ, Baiocchi RA, Vyas JM, Rhee KY, Hu PJ, Isales CM, Conlin PR, Kontos   CD, Melfe M, McDonald FS, Rockey DC, Williams CS.

JCI Insight. 2026 Aug 24;11(16):e195683. doi:   10.1172/jci.insight.195683. eCollection 2026 Aug 24.

PMID: 42635045      Free PMC   article. 

 

From   the pages of AllergyWatch. 

Joshi SR, Fineman SM, Lee GB, Otani I.

Ann Allergy Asthma Immunol. 2026 Sep;137(3):406-408. doi:   10.1016/j.anai.2026.06.023.

PMID: 42680241      No abstract   available.

 

"I   feel like you should buy an umbrella before it starts raining":   caregiver perspectives on illness inflection points in chronic obstructive   pulmonary disease. 

Smirnova N, Batieste T, Sullivan DR, Jamdar S, Lowers J,   Suen A, Murray C, Peterson C, Kavalieratos D.

Ann Am Thorac Soc. 2026 Sep 1;23(9):1313-1319. doi:   10.1093/annalsats/aaoag094.

PMID: 42152177     

 

The   Orphaned Science of Perinatal Pharmacology. 

Jain L.

Clin Perinatol. 2026 Sep;53(3):xvii-xix. doi:   10.1016/j.clp.2026.06.002. Epub 2026 Jun 29.

PMID: 42556990      No abstract   available.

 

Scholarly   Skills Series: How to Succeed in Writing Case Reports. 

Lal A, Pinto Taylor E, Kavalieratos D, Robbins-Welty GA.

J Palliat Med. 2026 Sep;29(9):1195-1200. doi:   10.1177/10966218261465073. Epub 2026 Jul 7.

PMID: 42415542     

 

Respiratory   Syncytial Virus Hospitalizations in Adults ≥50 Years of Age and Those With   Congestive Heart Failure or Chronic Obstructive Pulmonary Disease   Exacerbations, 2018-2020. 

Tippett A, Prasad PV, Begier E, Kim SS, Gibson T, Salazar   LW, Taylor M, Reese O, Ess G, Choi C, Ciric C, Taylor EG, De Castro K, Jadhao   S, Sun H, Hsiao HM, Gupta S, Li W, Stephens K, Hubler R, Liu Q, Swerdlow D,   Gessner BD, Uppal S, Liang C, Kalina W, Jodar L, Kamidani S, Yildirim I,   Rouphael N, Nelson KN, Anderson LJ, Rostad CA, Anderson EJ.

Clin Infect Dis. 2026 Sep 2;83(2):e416-e426. doi:   10.1093/cid/ciag134.

PMID: 41733233      Free PMC   article. 

 

Balanced   Fluid or 0.9% Saline in Children Treated for Septic Shock. 

Balamuth F, Weiss SL, Long E, Thompson GC, Artis AS,   Campos AB, Borland ML, Dalziel SR, Yock-Corrales A, Singh R, Williams A,   Mickiewicz B, Hickey CP, Fitzgerald JC, Laskin BL, Hickey RW, Eckerle M,   Alqurashi W, Alpern E, Ambroggio L, Badawy M, Baumer-Mouradian S, Berthelot   S, Clukies LD, Craig S, Curtis SJ, Davis AL, Duffy S, Eisenberg MA, Emsley   JG, Festekjian A, George S, Green R, Gripp KE, Jain PG, Jani S, Joubert GI,   Judge P, Kam A, Kochar A, Koutroulis I, Kwok MY, Lane RD, Lithgow A, Lloyd J,   Mansour K, McManemy JK, Morris C, Phillips N, Rao A, Rogers A, Sehgal A,   Shayan Y, Silverman J, Tan E, Uspal NG, Vance C, Whyte E, Huang J, Freedman   SB, Babl FE, Kuppermann N; PRoMPT BOLUS Investigators of the PECARN, PERC,   and PREDICT Networks.

N Engl J Med. 2026 Sep 3;395(9):870-881. doi:   10.1056/NEJMoa2601969. Epub 2026 Apr 24.

PMID: 42028918      Free PMC   article.      Clinical Trial.       

 

Uncovering   the mechanism of action of a historical antimicrobial against S. aureus  and A. baumannii. 

Orababa OQ, Furner-Pardoe J, Gale A, Anonye B, Ratcliff J,   Reddy N, Maset RG, Harrington NE, Subhaskaran S, Holden S, Diggle SP, Corre   C, Harrison F.

mSphere. 2026 Sep 3:e0049426. doi:   10.1128/msphere.00494-26. Online ahead of print.

PMID: 42690030      

 

Local   delivery of rhBMP-2 affects systemic metabolic response during healing of   critically-sized segmental defects in a rat model. 

Schwiebert EM, Strait LK, Moore SG, Gaul DA, Fernández FM,   Guldberg RE.

Bone. 2026 Oct;211:117990. doi:   10.1016/j.bone.2026.117990. Epub 2026 Jun 25.

PMID: 42349530      Free PMC   article. 

 

Paediatric   Drug Optimization for Sickle Cell Disease: priorities for research and   development in children. 

Masini T, Charnaud S, Hankins JS, Kityo C, Makani J,   Morris CR, Odame I, Ross AL, Segafredo G, Ubuguyu OS, Yaqub NO Jr, Were WM,   Penazzato M; PADO-SCD participants.

Lancet Child Adolesc Health. 2026 Oct;10(10):755-764. doi:   10.1016/S2352-4642(26)00159-8.

PMID: 42679830      Review.       

 

Project   Sickle Cure: A Prospective, International Observational Study of   Hematopoietic Cell Transplantation for Sickle Cell Disease. 

Guilcher GMT, Abraham A, Arnold SD, Camacho-Bydume C,   Duong J, Gillespie S, Haight A, Hulbert ML, Kumar N, Liu K, Mammen C, Mineyko   A, Morgan A, Ngwube A, Nickel RS, Roberts A, Schulte F, Sands S, Sharma A,   Horan JT, Stenger EO.

Eur J Haematol. 2026 Oct;117(4):1052-1060. doi:   10.1111/ejh.70240. Epub 2026 Jun 19.

PMID: 42322070      Free PMC   article. 

 

Secretory   Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized   for Vaso-Occlusive Pain Episodes. 

Korman R, Yasmine M, Hatabah D, Alzraikat N, Harris F,   Brown LA, Chonat S, Bakshi N, Rees CA, Dampier C, Morris CR.

Pediatr Blood Cancer. 2026 Oct;73(10):e70615. doi:   10.1002/1545-5017.70615. Epub 2026 Aug 4.

PMID: 42549972      Clinical Trial.       

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