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Recent Publications

Quarterly Updates: Recent Publications from CF@LANTA and CF-AIR Investigators

Secretory Expression and Purification of Respiratory Syncytial Virus G and F Ectodomain in Human Cells.Sankaranarayanan R, Ha B, Jadhao SJ, Anderson LJ.Methods Mol Biol. 2025;2948:127-135. doi: 10.1007/978-1-0716-4666-3_9.PMID: 40879906


Quantification of RSV Antibodies in Human Plasma by Enzyme Immunoassays.Sankaranarayanan R, Ha B, Jadhao SJ, Anderson LJ.Methods Mol Biol. 2025;2948:365-374. doi: 10.1007/978-1-0716-4666-3_23.PMID: 40879920


Association of 17q12-q21 Asthma Risk Locus with Clinical Severity of Infant Respiratory Syncytial Virus Infection.Turi KN, McKennan C, Rosas-Salazar C, Gebretsedik T, Newcomb DC, Thompson EE, Gern J, Chappell J, Anderson L, Ober C, Hartert T.Biomolecules. 2025 Jul 22;15(8):1056. doi: 10.3390/biom15081056.PMID: 40867500 


Sex-specific transcriptomic profiling reveals key players in bone loss associated with Alzheimer's disease.Gharpure M, Vyavahare S, Asante DM, Chen J, Zhong R, Cooley MA, Deak F, Lu XY, Isales CM, Fulzele S.Geroscience. 2025 Aug;47(4):5469-5480. doi: 10.1007/s11357-025-01535-7. Epub 2025 Jan 29.PMID: 39875754 


Integrative analysis of microbial 16S gene and shotgun metagenomic sequencing data improves statistical efficiency in testing differential abundance.Yue Y, Mao Y, Read TD, Fedirko V, Satten GA, Chen X, Zhan X, Hu YJ.J Am Stat Assoc. 2025 Aug 5:10.1080/01621459.2025.2516205. doi: 10.1080/01621459.2025.2516205. Online ahead of print.PMID: 40857503

Conserved cross-domain protein-to-mRNA ratios enable proteome prediction in microbes.Zhang M, Zhang C, Ramos A, Whitaker RJ, Whiteley M.mBio. 2025 Aug 13;16(8):e0141125. doi: 10.1128/mbio.01411-25. Epub 2025 Jul 24.PMID: 40704792

Stenotrophomonas maltophilia complex: A broadly distributed emerging pathogen.Crisan CV, Goldberg JB.PLoS Pathog. 2025 Aug 21;21(8):e1013422. doi: 10.1371/journal.ppat.1013422. eCollection 2025 Aug.PMID: 40839706 


AI in Palliative Care: A Scoping Review of Foundational Gaps and Future Directions for Responsible Innovation.Bozkurt S, Fereydooni S, Kar I, Chalmers CD, Leslie SL, Pathak R, Walling AM, Lindvall C, Lorenz K, Parikh R, Quest T, Giannitrapani K, Kavalieratos D.J Pain Symptom Manage. 2025 Aug 21:S0885-3924(25)00783-3. doi: 10.1016/j.jpainsymman.2025.08.009. Online ahead of print.PMID: 40849027 


Inhibition of AhR improves cortical bone and skeletal muscle function via preservation of neuromuscular junctions.Yu K, Vyavahare S, Alhamad D, Bensreti H, Ruan L, Tuladhar A, Dai C, Shaver JC, Tripathi A, Ding K, Pacholczyk R, Cooley MA, Zhong R, Johnson MH, Chen J, Bollag WB, Isales CM, Hill WD, Hamrick MW, Fulzele S, McGee-Lawrence ME.JCI Insight. 2025 Jul 15;10(16):e192047. doi: 10.1172/jci.insight.192047. eCollection 2025 Aug 22.PMID: 40663393


Lipid metabolism in age-related musculoskeletal disorders: insights into sarcopenia and osteoporosis.Lal S, Gunji S, Ahluwalia P, Kolhe R, Bollag WB, Hill WD, McGee-Lawrence ME, Isales CM, Fulzele S.BMC Biol. 2025 Aug 22;23(1):265. doi: 10.1186/s12915-025-02383-9.PMID: 40846955


Examining Help-Seeking Behavior in People Living Alone With Cognitive Impairment.Smith CP, Perkins MM, Hepburn KW, Kavalieratos D, Lowers J.J Appl Gerontol. 2025 Sep;44(9):1383-1391. doi: 10.1177/07334648241309478. Epub 2025 Jan 9.PMID: 39783638


Strategies for successful research recruitment and program implementation in pediatric emergency medicine.Calamaro JG, Hatabah D, Benedit L, Abdallah C, Akinsola B, Berkowtiz T, Bora N, Burger RK, Bryant JE, Cameron MN, Fisher G, Francois S, Grell R, Griffiths M, Gutierrez P, Heidari A, Hoyos A, Jain S, Jones K, Khan N, Konatham S, Korman R, Ling J, Little W, Luu V, Maziashvili G, Mawhinney K, McCloskey M, Middlebrooks L, Ng C, Perez E, Promer G, Reddy N, Rees CA, Rodriguez M, Sarnaik A, Simon HK, Wynn BA, Yasmine M, Morris CR.Acad Emerg Med. 2025 Sep;32(9):1024-1026. doi: 10.1111/acem.70038. Epub 2025 Apr 11.PMID: 40219584


Assessment of Glycemic Control Using Continuous Glucose Monitoring During Hospitalization and After Discharge for Older Adults.Kantipudi S, Idrees T, Castro-Revoredo I, Vellanki P, Castejon-Rosales E, Petty K, Peng L, Umpierrez GE.J Diabetes Sci Technol. 2025 Sep;19(5):1427-1428. doi: 10.1177/19322968251332656. Epub 2025 Apr 12.PMID: 40219823


A Non-Metaproteomics Researchers' View on Metaproteomics in Microbiome Research.Aho VTE, Clerbaux LA, Kupczok A, Tillett B, Garg N, Henderickx JGE.Proteomics. 2025 Sep;25(17-18):28-32. doi: 10.1002/pmic.202500019. Epub 2025 Apr 27.PMID: 40289407


The Scope of Clinical Practice of Inpatient and Outpatient Pediatric Palliative Care Within Pediatric Oncology.Park HS, DeGroote N, Lewis RW, Lee K, Lange A, Johnson K, Kavalieratos D, Brock KE.Pediatr Blood Cancer. 2025 Sep;72(9):e31832. doi: 10.1002/pbc.31832. Epub 2025 Jun 12.PMID: 40506667


Suppression of LKB1-mutant lung adenocarcinoma by natural killer cells from females.Fan Y, Jin R, Monterroza L, Liu X, Huang C, Marra A, Mo X, Fu H, Gilbert-Ross M, Marcus AI, Tirouvanziam R, Liu Y, Schneider F, Zhou W.J Natl Cancer Inst. 2025 Sep 1;117(9):1858-1867. doi: 10.1093/jnci/djaf138.PMID: 40511603


Molecular basis of Fab-dependent IgA antibody recognition by gut-bacterial metallopeptidases.Márquez-Moñino MÁ, Martínez Gascueña A, Azzam T, Persson A, Manzanares-Gomez A, Aguillo-Urarte M, Brown TT, Montero-Sagarminaga A, Lood R, Naegeli A, Connell SR, Sastre DE, Sundberg EJ, Trastoy B.EMBO J. 2025 Sep;44(17):4867-4898. doi: 10.1038/s44318-025-00518-w. Epub 2025 Jul 31.PMID: 40745064


Author Correction: A universal language for finding mass spectrometry data patterns.Damiani T, Jarmusch AK, Aron AT, Petras D, Phelan VV, Zhao HN, Bittremieux W, Acharya DD, Ahmed MMA, Bauermeister A, Bertin MJ, Boudreau PD, Borges RM, Bowen BP, Brown CJ, Chagas FO, Clevenger KD, Correia MSP, Crandall WJ, Crüsemann M, Fahy E, Fiehn O, Garg N, Gerwick WH, Gilbert JR, Globisch D, Gomes PWP, Heuckeroth S, James CA, Jarmusch SA, Kakhkhorov SA, Kang KB, Kessler N, Kersten RD, Kim H, Kirk RD, Kohlbacher O, Kontou EE, Liu K, Lizama-Chamu I, Luu GT, Luzzatto Knaan T, Mannochio-Russo H, Marty MT, Matsuzawa Y, McAvoy AC, McCall LI, Mohamed OG, Nahor O, Neuweger H, Niedermeyer THJ, Nishida K, Northen TR, Overdahl KE, Rainer J, Reher R, Rodriguez E, Sachsenberg TT, Sanchez LM, Schmid R, Stevens C, Subramaniam S, Tian Z, Tripathi A, Tsugawa H, van der Hooft JJJ, Vicini A, Walter A, Weber T, Xiong Q, Xu T, Pluskal T, Dorrestein PC, Wang M.Nat Methods. 2025 Sep;22(9):1995. doi: 10.1038/s41592-025-02785-1.PMID: 40781363


Targeted Proteomic Analysis of Sickle Cell Disease Patients With Elevated Tricuspid Regurgitation Velocity.Babu V, Little JA, Morris CR, Machado R, Gibbs S, Kato GJ, Gordeuk VR, Gladwin MT, Zhang Y, Nouraie SM.Proteomics Clin Appl. 2025 Sep;19(5):e70019. doi: 10.1002/prca.70019. Epub 2025 Aug 11.PMID: 40785364


Maternal factors associated with plasma concentrations of endocrine-disrupting persistent organic pollutants including PFAS among Hispanic women from pregnancy to the post-delivery period.Qiu C, Chen W, Kang N, Liao J, Osazuwa N, Schimke C, Sjodin A, Calafat AM, Botelho JC, Jones D, Buchanan T, Xiang AH, Chen Z.Environ Int. 2025 Sep;203:109723. doi: 10.1016/j.envint.2025.109723. Epub 2025 Aug 11.PMID: 40816047


Newborn Screening: The Time Is Now.Jain L.Clin Perinatol. 2025 Sep;52(3):xv-xvi. doi: 10.1016/j.clp.2025.06.012. Epub 2025 Jul 1.PMID: 40850720


Mechanosensing Pathways in the Progression of Pulmonary Fibrosis.Nieves EB, García AJ.Curr Opin Biomed Eng. 2025 Sep;35:100598. doi: 10.1016/j.cobme.2025.100598. Epub 2025 May 17.PMID: 40895343


Survey Validation of Exercise and Body Composition Testing and Exercise Training Programs for People With Cystic Fibrosis: A Delphi Study.Alotaibi NZ, Lein DH, Yuen HK, Harris RA, Krick S, Plaisance EP, Lowman JD.Pediatr Pulmonol. 2025 Sep;60(9):e71262. doi: 10.1002/ppul.71262.PMID: 40911388


Metabolic dysregulation in Alzheimer's disease: A brain metabolomics approach.Hüls A, Tan Y, Casey E, Li Z, Gearing M, Levey AI, Lah JJ, Wingo AP, Jones DP, Walker DI, Wingo TS, Liang D.Alzheimers Dement. 2025 Sep;21(9):e70528. doi: 10.1002/alz.70528.PMID: 40931996


Development of a microneedle patch for delivery of mRNA-lipid nanoparticles.Sakers SH, Reddy BPK, Fiduccia G, Byrne KE, Stén I, Kim J, Radmand A, Dahlman JE, Prausnitz MR.Drug Deliv Transl Res. 2025 Sep 2. doi: 10.1007/s13346-025-01964-z. Online ahead of print.PMID: 40892321


Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain.Gwarzo I, Coleman KD, McKinley K, Ellison AM, Alpern ER, Corboy J, Hariharan S, Topoz I, Wurtz M, Nielsen B, Cook LJ, Morris CR, Brandow AM, Campbell AD, Liem RI, Nuss R, Quinn CT, Thompson AA, Villella A, King AA, Baumann A, Frankenberger W, Brousseau DC.JAMA Pediatr. 2025 Sep 2:e252967. doi: 10.1001/jamapediatrics.2025.2967. Online ahead of print.PMID: 40892426


Circular RNA RORβ regulates TGFβR1 in alcohol-induced fibroblast-to-myofibroblast differentiation.Sueblinvong V, Fan X, Kartmouty-Quintana H, Kopp BT, Kang BY.Sci Rep. 2025 Sep 2;15(1):32295. doi: 10.1038/s41598-025-15040-6.PMID: 40897735


Nebulization of an mRNA-encoded monoclonal antibody for passive immunization of foals against Rhodococcus equi.Legere RM, Ott JA, Poveda C, Vanover D, Borba KER, Yeon Joo J, Martin CL, da Silveira BP, Bray JM, Landrock K, Wright GA, Blazier JC, Hillhouse AE, Benham-Duret AL, Mistretta B, Klein RL, Thompson SM, Woolums AR, Criscitiello MF, Berghman LR, Bordin AI, Santangelo PJ, Pollet J, Cohen ND.Mol Ther. 2025 Sep 3;33(9):4175-4192. doi: 10.1016/j.ymthe.2025.06.025. Epub 2025 Jun 14.PMID: 40518672


Multipass CCS Refiner: A Web Application for Accurate Collision Cross Section Calibration in Cyclic Ion Mobility-Mass Spectrometry.Gier EC, Leontyev D, Fernández FM.J Am Soc Mass Spectrom. 2025 Sep 3;36(9):2000-2004. doi: 10.1021/jasms.5c00199. Epub 2025 Aug 19.PMID: 40828913


Musculoskeletal Complications in COVID-19: Exploring the Role of Key Biomarkers.Patel S, Foster C, Patel K, Hunter M, Isales CM, Fulzele S.Int J Mol Sci. 2025 Sep 3;26(17):8569. doi: 10.3390/ijms26178569.PMID: 40943488


Quantitative modeling of multi-signal quorum-sensing maps environment to bacterial regulatory responses.Thomas S, El-Zayat AS, Gurney J, Rattray J, Brown SP.PLoS Biol. 2025 Sep 4;23(9):e3003316. doi: 10.1371/journal.pbio.3003316. eCollection 2025 Sep.PMID: 40906612

Meclizine rescues cardiac function and mitochondrial ultrastructure by ATP- and glycolysis-independent mechanisms in a genetic model of mitochondrial energy dysfunction.Ghazal N, Huang B, Shoemaker LJ, Faundez V, Kwong JQ.bioRxiv [Preprint]. 2025 Sep 7:2025.09.03.674000. doi: 10.1101/2025.09.03.674000.PMID: 40950028


Combatting resistance: natural products as tools to drive the discovery of untapped antibiotic targets.Hedges MR, Di Carlo CM, Wuest WM.Chem Commun (Camb). 2025 Sep 11;61(74):14039-14058. doi: 10.1039/d5cc03863d.PMID: 40844298


Vanadyl sulfate supplementation alters the intestinal microbiome and bile acid metabolism.He X, Dennis KK, Jarrell ZR, Ly VT, Go YM, Jones DP.Toxicol Appl Pharmacol. 2025 Sep 11;505:117548. doi: 10.1016/j.taap.2025.117548. Online ahead of print.PMID: 40945867


Concentrations of Adrenocorticotropic Hormone (ACTH1-24) Too Low to Effect Cortisol Enhance Osteogenesis In Vitro and In Vivo.Tourkova IL, Rankin RA, Larrouture QC, Dobrowolski SF, Isales CM, Blair HC.Am J Physiol Endocrinol Metab. 2025 Sep 12. doi: 10.1152/ajpendo.00084.2025. Online ahead of print.PMID: 40938810


Type 2 diabetes subtypes classification: a global reckoning with heterogeneity.Jagannathan R, Staimez LR, Narayan KMV.Lancet Diabetes Endocrinol. 2025 Sep 12:S2213-8587(25)00256-6. doi: 10.1016/S2213-8587(25)00256-6. Online ahead of print.PMID: 40953573


A Plasma Metabolic Signature to Diagnose Pulmonary Tuberculosis and Monitor Treatment Response.Collins JM, Bobosha K, Narayanan N, Gandhi NR, Day CL, Rengarajan J, Kempker RR, Lau MSY, Nellis M, Tukvadze N, Shah NS, Brust JCM, Nizam A, Ismail NA, Kauffman KD, Sakai S, Jones DP, Barber DL, Ziegler TR, Ernst JD, Blumberg HM, Wassie L; Tuberculosis Research Unit - Role of Antigen-Specific T Cell Responses in the Control of TB (TBRU-ASTRa).J Infect Dis. 2025 Sep 15;232(3):578-587. doi: 10.1093/infdis/jiaf240.PMID: 40338044


Clinical Correlates of Insomnia Symptoms in Young Children with Autism Spectrum Disorder.Wenzell ML, Pulver SL, Scahill L, Davidson T, Rajagopal S, Gillespie S, Huang T, Griggs S, Roark C, Patil M, Patel M, Sharp WG.J Pediatr. 2025 Sep 15:114812. doi: 10.1016/j.jpeds.2025.114812. Online ahead of print.PMID: 40962108


Noninvasive Markers of Hepatic Steatosis and Fibrosis Following Integrase Strand-Transfer Inhibitor Initiation in Women With HIV.Yu MA, Gerig L, Mehta CC, Musonge-Effoe J, Alvarez JA, Ofotokun I, Sheth AN, Ali MK, Ziegler TR, Yang Q, Spence AB, Alcaide ML, Dumond JB, Abraham AG, French AL, Augenbraun M, Anastos K, Price JC, Tien PC, Lahiri CD.Clin Infect Dis. 2025 Sep 16;81(2):304-313. doi: 10.1093/cid/ciaf049.PMID: 39899358


Prenatal Nitrogen Oxide (NOx) and Its Potential Impact on Infant Metabolism during the First Month of Life: Evidence from Two Distinct Cohorts─The Atlanta African American Maternal-Child Cohort and the Southern California Mother's Milk Study.Holzhausen EA, Tan Y, Young N, Jones RB, Tang Z, Sarnat JA, Lurmann F, Chang HH, Tran V, Jones DP, Goran MI, Dunlop AL, Liang D, Alderete TL.Environ Sci Technol. 2025 Sep 16;59(36):19131-19145. doi: 10.1021/acs.est.5c04955. Epub 2025 Sep 4.PMID: 40906902


Lipid A mimetic BECC438 potentiates durable and balanced antibody responses in an ovalbumin murine model of vaccination.Harberts EM, Fields JK, Hunat JCS, Otteni DM, Gardner FM, Varisco DJ, Sundberg EJ, Snyder GA, Ernst RK.Immunohorizons. 2025 Sep 17;9(10):vlaf038. doi: 10.1093/immhor/vlaf038.PMID: 40972648


Relationship between skeletal muscle indicators and clinical outcomes in cystic fibrosis is modified by adiposity and CFTR modulator use: A cross-sectional analysis.Gonzalez Ramirez LA, Suppakitjanusant P, Burley TM, Zaveri S, Stecenko AA, Hunt WR, Harris RA, Stallings VA, Ivie EA, Driggers C, Binongo JN, Ziegler TR, Alvarez JA.Am J Clin Nutr. 2025 Sep 17:S0002-9165(25)00536-2. doi: 10.1016/j.ajcnut.2025.09.019. Online ahead of print.PMID: 40972870


Genome-Wide Association Study of Hypoglycemia in Adults With Diabetes in the Million Veteran Program.Raghavan S, Litkowski E, Jensen A, Charest B, Wang Z, Hui Q, Chen HC, Rhee MK, Leong A, Meigs JB, Lange L, Lange E, Reaven P, Hung A, Zhou J, Sun YV, Phillips LS; Million Veteran Program.Diabetes. 2025 Sep 19:db250304. doi: 10.2337/db25-0304. Online ahead of print.PMID: 40971195


Comparative Analysis of Clinical Outcomes Related to Telehealth and In-Person Encounters Among Older Veterans with Diabetes.Syed Q, McGwin G, Johnson T 2nd, Phillips LS, Khakharia A, Echt KV, Rhee M, Vaughan CP.J Gen Intern Med. 2025 Sep 22. doi: 10.1007/s11606-025-09871-2. Online ahead of print.PMID: 40983833


Transformative Research in Cystic Fibrosis.Sorscher EJ.N Engl J Med. 2025 Sep 25;393(12):1231-1234. doi: 10.1056/NEJMcibr2510197. Epub 2025 Sep 11.PMID: 40934189

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